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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NT5DC1 All Species: 15.76
Human Site: T389 Identified Species: 34.67
UniProt: Q5TFE4 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5TFE4 NP_689942.2 455 51845 T389 S V L G L E N T E D S L V Y T
Chimpanzee Pan troglodytes XP_518703 455 51825 T389 S V L G L E N T E D S L V Y T
Rhesus Macaque Macaca mulatta XP_001112048 455 51828 T389 S V W G L E N T E D S L V Y T
Dog Lupus familis XP_532271 471 53423 T405 S V S G L E N T E D S L V Y T
Cat Felis silvestris
Mouse Mus musculus Q8C5P5 467 53076 S399 G R G R A E D S V V Y T W S S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507572 133 15081 F68 G S D F A D L F D I V I T N A
Chicken Gallus gallus XP_419778 454 52040 E388 L P G L E N A E E T L V R T W
Frog Xenopus laevis Q6GN91 499 58768 K417 Q E T R D L T K T M F N R Q F
Zebra Danio Brachydanio rerio NP_001098413 461 52643 D390 Q W G S Y F V D V Q K T E G E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001121742 508 59601 S443 E E S C S S F S K D G K K Y D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001197549 242 27677 Y177 L E C F G L V Y K R E N F A D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 98.2 83 N.A. 78.5 N.A. N.A. 24.1 75.1 21.4 62 N.A. N.A. 25.7 N.A. 24.4
Protein Similarity: 100 100 99.1 87 N.A. 86 N.A. N.A. 27.2 86.3 39.4 76.7 N.A. N.A. 42.1 N.A. 34.5
P-Site Identity: 100 100 93.3 93.3 N.A. 6.6 N.A. N.A. 0 6.6 0 0 N.A. N.A. 13.3 N.A. 0
P-Site Similarity: 100 100 93.3 93.3 N.A. 26.6 N.A. N.A. 20 13.3 0 0 N.A. N.A. 26.6 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 19 0 10 0 0 0 0 0 0 10 10 % A
% Cys: 0 0 10 10 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 10 10 10 10 10 46 0 0 0 0 19 % D
% Glu: 10 28 0 0 10 46 0 10 46 0 10 0 10 0 10 % E
% Phe: 0 0 0 19 0 10 10 10 0 0 10 0 10 0 10 % F
% Gly: 19 0 28 37 10 0 0 0 0 0 10 0 0 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 10 0 10 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 10 19 0 10 10 10 0 0 % K
% Leu: 19 0 19 10 37 19 10 0 0 0 10 37 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 10 37 0 0 0 0 19 0 10 0 % N
% Pro: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 19 0 0 0 0 0 0 0 0 10 0 0 0 10 0 % Q
% Arg: 0 10 0 19 0 0 0 0 0 10 0 0 19 0 0 % R
% Ser: 37 10 19 10 10 10 0 19 0 0 37 0 0 10 10 % S
% Thr: 0 0 10 0 0 0 10 37 10 10 0 19 10 10 37 % T
% Val: 0 37 0 0 0 0 19 0 19 10 10 10 37 0 0 % V
% Trp: 0 10 10 0 0 0 0 0 0 0 0 0 10 0 10 % W
% Tyr: 0 0 0 0 10 0 0 10 0 0 10 0 0 46 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _